What is Preimplantation Genetic Screening?

 

The couple who opt for IVF for a child generally wonders if their child would be genetically fit. This stress may be more when intended couples are genetically challenged and think that their child should not have these genetic issues. So in this blog, we are going to reveal the new advanced technique to ensure your child will be genetically fit.

PGS or Preimplantation Genetic Screening is a genetic test that has made IVF most successful than ever! Assisted reproductive treatments can now show infertility and genetic conditions more effectively than before. Couples and individuals affected by a genetic disorder can conceive a biological child. Couples or individuals at increased risk for having embryos with abnormal chromosomes are the best candidates for PGS. These include:

1. Advanced maternal age above 35
2. Recurrent miscarriages, or
3. Previous failed IVF attempts

In a normal person, there are 23 pairs or 46 chromosomes present. Aneuploidy is the condition in which an embryo contains one more or one less chromosome. That means, there are 45 or 47 chromosomes present instead of the normal 46. PGS (Preimplantation Genetic Screening) screens embryos for chromosomal abnormalities (aneuploidy).

Process

PGS test for chromosomal abnormalities. On day 3 or day 5 of embryo development, a few cells are removed from embryos created with IVF. The DNA of these cells will be evaluated for chromosomal defects. At this stage, the embryologist can determine the gender (sex) of the embryos. If parents are interested in family balancing, then only embryos of the desired sex will be transferred to the mother’s uterus.

It diagnoses single gene mutations associated with genetically inherited diseases, e.g. sickle cell anemia, muscular dystrophy, Huntington’s Disease, Fragile X syndrome, cystic fibrosisand many more.

The success rate of PGS

The chance of a successful outcome with PGS in joint with IVF treatment depends on whether any and how many of the embryos produced in an IVF cycle have a normal PGS result. According to the reports a live birth rate is high 60% to 80% when an elective single frozen embryo is transferred in a subsequent cycle. These success rates are very encouraging as most couples who undergo PGS and IVF are at higher risk of producing chromosomally abnormal embryos such as advanced maternal age, previous IVF failures, or recurrent pregnancy losses.

So, from all the above context, we can ensure you if you are worried about any means for IVF and procedures. You can visit the renowned Asha IVF and Fertility Centre, PGS clinic in Faridabad.

Source Link: https://drasthachakravarty.com/what-is-preimplantation-genetic-screening/

Age and fertility in men and women

 There are many causes behind the declining rate of fertility today. Among the most important ones is age, which can play a big role in conception. Doctor Astha Chakravarty from Asha IVF & Fertility Centre, a medical expert on gynecology and fertility, discusses how aging affects women’s fertility and that of men.

You can’t control your age. The reason why many women & men have babies later in life is that they are not as settled as they think they will be in the future (for instance with money or housing), they do not want to have children in the beginning or they do not have a partner with whom to have a child.

Age and egg quality

The eggs a woman has at birth are all she will ever have, at Best Gynecologist in Faridabad when a patient visits they ensure to make them aware about every aspect like A woman’s eggs continue to age with her, and they gradually decrease both in quantity and quality as she ages. This is why women over 35 years of age have a lower likelihood of having a baby over time as well.

When women are in their 20s and early 30s, they are not necessarily ready to start a family for whatever reason.

Age and sperm quality 

The average man makes millions of new sperm each day, but older men have fewer healthy sperm than younger men. Ideally, between the ages of 20 and 80, sperm motility (their ability to move toward an egg) and the quantity of semen (the fluid in which sperm reside) decrease steadily.

What if my reproductive partner is older?

We have commonly heard that the main reason for not being able to start a family is female, but that is not entirely accurate. In the same way that women’s ability to have children declines with age, so does the ability of men to have one as well.

In cases where the male partner is over 40, it may be harder for the female partner to conceive, especially if she is also 40.

Dr. Asha Chakrabarty, known for providing the Best Surrogacy in Faridabad also believes,  From her experience, she shares a few other reasons below why older men have a lower chance of being a father. 

• Less desire for sex.
• Sperm of poor quality.
• Hormones associated with the male sex are lower.

For the best IVF experience, make an appointment at Asha IVF & fertility centre or visit us to book your appointment with the Best Gyanecologist in Faridabad.